Is Progeline A Real Miracle Or A Myth? (2023)

Dear all glow getters! We know that it has always been a struggle to pay for expensive skincare. Especially, the product that is effective yet outrageous and has priced ingredients. In case you are looking for something that will help your wrinkles go away and skin magically transformed, then there is a product that seems too good to be true. It’s called “Progeline Cream.”

You must now wonder what is Progeline and how it works? Well, it is described as “an anti-aging cream. It supposedly reduces fine lines, wrinkles, or other signs of aging.” Progeline is a great thing to include in your daily skincare routine. And, you might get some marginal benefits as the company claims. But who knows!

What Is Progeline?

Progeline cream is a bio-engineered peptide. It combines glycerin, water, dextran, and trifluoroacetyl tripeptide into one mixture. Progeline is a special and equally unique ingredient familiarized by Lucas Meyer Cosmetics. He defines it a biomimetic peptide derived from Elafin. Usually, the Progeline is used by the company named Skin Perfection. This institution formulates and creates all-natural skincare products made with dermatology-grade ingredients.

This Progeline Peptide is also known as firming serum. It is officially sourced from Canada. This biomimetic complex enhances our protein matrix. Progeline is similar to Botox. Why? Because, it also mimics the freezing of your facial muscles. And, yes, lessens the appearance of wrinkles, too. It’s temporary and not a permanent fix. But, it makes your skin really firm and wrinkles less visible. Progeline can add so much benefit to your own skincare routine no matter what your skin type, tone, or skin concern.

When used correctly, peptides can bring about hydration to the skin. It can help even out the skin’s tone and complexion. Moreover, they can help trigger collagen and elastin production. These can lead to a reduction in fine lines and wrinkles.

Is Progeline Cream a Costly Option?

The peptides don’t need to cost the earth. If you reach for super expensive Bougiee Cosmetics and luxury peptides, thinking they are the ones that can give you the most benefit, then this just isn’t the case. There are some really great affordable peptide options. For instance, The Ordinary, Niod and Hylamide. The bottle is small in size but since it’s used in other products. Thus, we can say the bottle generally lasts much longer.

How Should You Take Progeline?

Progeline is honestly one of those miracle ingredients. And, we will encourage every person to explore. They’re not the easiest thing to incorporate in your own skincare routine. Especially because there is a lot of wrong information present out there about what you can and cannot use peptides alongside.


Nowadays, you can absolutely use most over-the-counter retinol. You can use other things like Differin Adapalene and Tretinoin alongside peptides, too. The same goes for vitamin C. You just have to make sure that you are not using them directly next to each other, and it all comes down to pH. Peptides can be pH sensitive. Therefore, you need to ensure that you’re applying them onto the skin. Your skin’s natural pH is roughly 5 or 5.5. If you use exfoliating acids and vitamin C, which tend to have a lower pH first, then use a nice toner or a hydrating mist. it will just rebalance the skin and also bring a bit of freshness back.

You can add it to a hyaluronic acid-based face cream or serum. As far as the concentration is concerned, it is about 18 drops of Progeline for 1 ounce of the hyaluronic acid serum.

How does Progeline Works?

As our age increases, our collagen levels decrease. So including a peptide in any anti-aging routine is honestly a must, and ultimately you will see some fantastic benefits. When it is used in a variety of skincare products, it sends necessary signals to your body to reduce signs of aging. This comprises preventing saggy skin and diminishing wrinkles’ appearance. Moreover, it has a role in making skin more hydrated and firm. Peptides are one of the best ways of getting hydration back into the skin.

Using copper peptides specifically can really help dial up the collagen production rate in the skin. It gives skin what it needs to produce collagen and amps it up. It leads to the skin having more of its own collagen.

Significant Benefits of Progeline for Skin

One of the best and quickest benefits you will see of peptides is hydration. They fairly give so much nourishment to the skin. You’ll feel an instant lift, lots of the tight feeling in the skin, and miraculously it all happens within about 10 to 15 seconds of applying the product. Studies have shown that peptides can help press pigment formation. Further, they help eradicate some of the hyperpigmentation. Its continuous use will reduce the fine lines and wrinkles. It will make skin firmer and bring back the elasticity that it was starting to lose.

Are there any Drawbacks of Progeline?

Peptides are worth investing in for the long haul benefits. When you first apply the product, you will get more hydration to the skin. It will offset some dryness. So, you get a little bit of a quick win from introducing a peptide into your routine. Generally, it takes between four and five months for noticeable results.

(Video) The ONLY anti-aging cream that works! - according to science

No clinical trials are listed on the official website. Only very few online Progeline reviews serve as testimonials.

You cannot apply Progeline directly to the skin. You have to mix it with another skincare cream.

There is a possibility that you may develop a rash or burning sensation

Why Is Progeline Considered a Myth?

Now the question comes, “does Progeline really work?”

The skincare industry generally tricks the audience by first highlighting a skin problem and then claiming to treat it. Trade names also play a vital role in selling because they resemble the skin problem name you claim to cure. SAME TRICK IS USED FOR PROGELINE! So, why it has not been put into the limelight before? Well, people having a rare Hutchinson-Gilford progeria syndrome only need to worry about the overwhelming effects of progerin. If you don’t have it and are not particularly too aged, then your cells shouldn’t react to progerin. Meaning thereby, Progeline would not be of any help to you.

Unfortunately, Progeline reviews are not readily available. The obtainable ones are, however, positive. Online recommendations concerning the product are difficult to find. Scientists disagree, too! They state that the research is based exclusively on lab reports. It means, there is no definite data supporting the product’s usage. Therefore, we are not confident about the efficacy of Progeline. Furthermore, since we’re not doctors, the material available in this article should be used for informational purposes only.

Another critical point to mention here is that fluoride is not present in our proteins. Our bodies are not accustomed to fluorinated peptides. It is difficult to comprehend how the peptides developers have concluded to prevent cell senescence. Examining synthetic peptides in the scientific literature produced no fruitful results either.

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We are advising you to be cautious because there are risks associated with Progeline that you may not have thought about. It is used in minute concentrations along with other skincare products. Most of Progeline is water, glycerol, and dextran. If any kind of peptide is present there, it will be removed by your body somehow. In the end, you’ve lost money. Nonetheless, if you choose to accept whatsoever you read on the internet as accurate, then this is unquestionably your mistake!

The Best Progeline Peptide

Skin Perfection – Firming Serum Trifluoroacetyl Tripeptide-2 Booster

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Mila Moursi – Lifting and Anti-Aging Serum, Face Lift Firming Cream with Progeline Peptides

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(Video) MiamiMD face cream review (after 5 days use)

Garden of Wisdom – Progeline Peptide Repair Serum

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Is progeline a real thing? ›

Progeline is an ingredient by Lucas Meyer Cosmetics that's described as a biomimetic peptide derived from Elafin. More specifically, as Guanche says, "Progeline cream is a bio-engineered peptide that combines glycerin, water, dextran, and trifluoroacetyl tripeptide into one mixture."

How can I reduce progerin naturally? ›

The buildup of progerin, an abnormal protein, interferes with normal cell functions and can cause early cellular aging. A substance in broccoli called sulforaphane can help break down progerin.

What does progeline do to your skin? ›

When progeline is used in skincare products, it can send necessary signals to your body to reduce signs of aging. This includes preventing saggy skin, minimizing wrinkles' appearance, and making our skin more hydrated and firm.

What is the most effective anti-aging procedure? ›

Botox and Xeomin are two of the most effective treatments available for wrinkles on the market. They're also more cost-effective and less risky than options such as a surgical facelift. Results typically appear within days after treatment and last for months.

What is the best natural treatment for aging skin? ›

But if you would like to slow the signs of aging on your face, there are natural ways to do so.
  • Wear sunscreen. ...
  • Limit your sugar intake. ...
  • Cut out smoking. ...
  • Use coconut oil. ...
  • Boost your beta carotene. ...
  • Try lemon balm leaf tea. ...
  • Switch up your sleep position. ...
  • Wash your face regularly.
Jan 23, 2018

Is there a vitamin that tightens skin? ›

Vitamins A, C and E

Vitamin A helps to hydrate the lower layer of skin, vitamin C preserves and protects skin-firming fibers such as collagen and elastin, and vitamin E safeguards skin from sun damage. To employ this powerful protection for your skin, eat more leafy greens and colorful fruits and vegetables.

How do I stop progerin protein? ›

Studies have shown a decrease in progerin protein levels by treatment with rapamycin or sulforaphane, by activating its clearance via autophagy [47, 48]. In addition, treatment with retinoids down-regulate total LMNA gene expression and decrease progerin expression in HGPS cells [49–51].

What increases progerin? ›

Research data indicate that UVA induces progerin by alternative splicing of the LMNA gene transcript. Previous results showed that a short UVC ultraviolet radiation causes the alternative splicing of genes involved in apoptosis and cell proliferation [22].

What protein tightens Crepey skin? ›

In a new paper published in Nature, a research team found that a collagen protein called COL17A1 plays a key role in maintaining youthful skin. Declining levels of this protein over time cause our skin to develop wrinkles, sag, and lose its elasticity, according to the paper.

Can I rebuild collagen in my face? ›

So what's the best way to rebuild collagen in your face? Tretinoin, a prescription-grade retinoid, is an excellent treatment for rebuilding collagen. Almost 30 years ago, a small study showed that tretinoin application increases collagen by up to 80% in the skin after 1 year of treatment.

What destroys collagen in the face? ›

Ultraviolet rays, aka sunlight, cause collagen to break down faster. With sun exposure, those UV rays damage the skin by entering the dermis (the second and thickest layer of our skin) which causes collagen to break down faster.

Can you regrow collagen in your face? ›

How can I naturally rebuild collagen? You can naturally support the collagen production process by using topicals such as vitamin C and retinol, collagen peptide supplements, eating a nutrient rich diet, and avoiding habits that damage the collagen (such as poor sleep and sun exposure.)

What is proven to reverse aging? ›

Is it possible to reverse aging? You cannot wholly reverse aging—it's a normal part of life. However, you may be able to slow it down and help prevent age-related diseases by adopting a healthy lifestyle. That includes habits like eating a healthy diet, wearing sunscreen every day, and exercising (Shanbhag, 2019).

Can anything reverse aging skin? ›

Of course, you can't reverse the signs of aging completely. You can go the nonsurgical route and add firming creams or facial exercises to your skincare routine. There are also cosmetic procedures that provide quicker results, such as laser surfacing or ultrasound skin tightening.

How can I look 20 years younger naturally? ›

19 Easy Ways to Look Younger, According to Experts
  1. Use a Moisturizer, Then Foundation. e.l.f. ...
  2. Try a Collagen-Based Face Cream. Elemis. ...
  3. Use a concealer for dark circles. Estée Lauder. ...
  4. Keep your eye makeup simple. Urban Decay. ...
  5. Curl those lashes. ULTA. ...
  6. Apply SPF Daily. Vichy. ...
  7. Take your time removing your makeup. Clinique.
Nov 4, 2022

What is the secret to stop aging? ›

Get enough sleep, protect your skin with sunscreen, eat a balanced diet, exercise, and manage your stress. Those are only some of the many ways you can take care of your body as you go through the natural process of aging. If you take care of yourself, your body will thank you in the long run.

What makes old skin look younger? ›

Skin brightening treatments, like Microdermabrasion, Light Peels, Micro Laser Peels, or the Clear & Brilliant Laser treatment all help patients to look 10 years younger or more, with just a few treatments. These treatments can be used in order to combat the signs of aging in the face, such as: Wrinkles. Age spots.

How can a 70 year old woman look younger? ›

In addition to sleeping on Blissy silk pillowcases, taking good care of your health can help you look and feel younger as you age. This involves eating nutritious foods, exercising regularly, drinking plenty of water, and making sure to get enough sleep.

What tightens skin the fastest? ›

Laser resurfacing This is the most effective procedure for tightening loose skin.

Can Crepey skin be reversed? ›

A plastic surgeon can remove the crepey looking skin, giving your body a more tightened appearance. Crepey skin shouldn't dictate how you see yourself in the mirror when there are so many options to improve its appearance.

Which protein is best for anti aging? ›


As you age, the production of collagen — a protein that helps maintain skin structure — slows, leading to accelerated signs of aging like wrinkles. Some research suggests that supplementing with collagen may reduce signs of aging, including wrinkles and dry skin ( 16 ).

What is the protein that causes rapid aging? ›

The gene, known as lamin A (LMNA), makes a protein necessary for holding the center (nucleus) of a cell together. When this gene has a defect (mutation), an abnormal form of the lamin A protein called progerin is produced and makes cells unstable. This appears to lead to progeria's aging process.

What foods slow down aging? ›

Foods to Favor
  • Romaine lettuce. It's high in vitamins A and C, which curb inflammation. ...
  • Tomatoes. They're rich in a nutrient called lycopene. ...
  • Salmon. It's high in omega-3 fats, which fight inflammation. ...
  • Lentils and beans. These are good sources of protein and are loaded with fiber and nutrients. ...
  • Oatmeal.
Sep 22, 2014

Where does progerin accumulate? ›

Progerin accumulates at the inner nuclear lamina and disrupts its properties causing the characteristic nuclear blebbing and a variety of cellular defects, including epigenetic modifications, senescence, and DNA repair deficiency (Kubben and Misteli, 2017).

How can I look 10 years younger naturally? ›

How to Look 10 Years Younger, Instantly
  1. Use a Hydrating Mask. For tighter, glowing skin, put on a hydrating mask for ten minutes. ...
  2. Choose a Luminous Foundation. ...
  3. Lighten Your Hair a Bit. ...
  4. Wear a Ponytail. ...
  5. Exfoliate (But Don't Overdo It) ...
  6. White Out Your Waterline. ...
  7. Finish Your Look With a Mineral Mist.

What vitamin is lacking for Crepey skin? ›

vitamins A, C, D, and E. omega-3 fatty acids.

Does Vaseline help Crepey skin? ›

According to Zeichner, loss of hydration and the resulting inflammation worsens crepey skin. He recommends looking for purified petrolatum in your moisturizer, as in Vaseline's popular lotion. It protects the skin's barrier, prevents water loss, hydrates and plumps thin skin.

What stimulates collagen in face? ›

Slather on a vitamin C serum in the morning. The vitamin is an antioxidant that protects the collagen in your skin against UV damage, says Chwalek. More than that, she says, it triggers collagen formation and stabilizes the collagen proteins in skin.

Does caffeine destroy collagen? ›

"It's worth remembering that coffee doesn't destroy collagen, it inhibits its production," says nutritional therapist at the Pulse Light Clinic, Lisa Borg.

Does drinking collagen reverse aging? ›

Current research reveals that collagen use could result in a reduction of wrinkles, rejuvenation of skin, and reversal of skin aging [16], which may improve skin hydration and elasticity [17].

What puts collagen back into skin? ›

Eating foods rich in vitamin C and amino acids can increase the levels of hyaluronic acid and collagen in the body as both are important for skin. Foods such as oranges, red peppers, kale, Brussels sprouts, broccoli, and strawberries are all rich in vitamin C.

What food has highest collagen? ›

The following three foods contain high levels of collagen:
  1. Bone Broth. Bone broth is made by simmering animal bones and connective tissue for an extended period of time. ...
  2. Fish With the Skin On. Fish are an excellent source of collagen from food, as long as you leave the skin on. ...
  3. Chicken.
Dec 7, 2022

Are eggs high in collagen? ›

Eggs don't contain fully synthesized collagen; however, egg whites are a rich source of proline, one of the two amino acids needed to synthesize collagen in the human body. They also contain some glycine. Pair eggs with foods high in vitamin C, copper, and zinc.

Can collagen reverse sagging skin? ›

Does Collagen Tighten Saggy Skin? Studies have indicated that supplemental collagen is beneficial for skin health, including tightening sagging skin (known as elasticity), boosting hydration, and lessening the appearance of wrinkles.

Does collagen lift sagging skin? ›

Collagen's role in the body

Collagen is a protein that serves as one of the main building blocks for your bones, skin, hair, muscles, tendons, and ligaments. "Collagen is what keeps our skin from sagging, giving us that plump, youthful look," says dermatologist Dr. Ohara Aivaz.

Why am I aging so fast all of a sudden? ›

This is called extrinsic aging. As a result, premature aging can set in long before it was expected. In other words, your biological clock is more advanced than your chronological clock. Controllable factors such as stress, smoking and sun exposure can all play a role in expediting extrinsic aging.

What makes you age slower? ›

From getting enough physical activity to limiting alcohol and stress, these habits reduce the risk of chronic disease and slow the aging process – helping you look and feel your best for years to come.

What makes a woman look younger naturally? ›

Drinking enough water each day replenishes your skin's tissue and cells, allowing for younger and healthier looking skin. Another key to maintaining a youthful appearance is to simply get some rest! When you sleep, your body continuously releases hormones that promote cell turnover and renewal.

At what age does your face change most? ›

Most people begin to notice a shift in the appearance of their face around their 40's and 50's, with some also noticing a change in their 30's. But with these physical changes brought on by aging also comes a change in the appearance of our face - Luckily, there is treatment available.

What does Gwyneth Paltrow use on face? ›

“I always start with our GoopGlow Jelly Cleanser,” Paltrow says. “It's an exfoliator and leaves the skin feeling amazing. The cleanser has an amazing pillowy jelly texture and has exfoliating beads in it that are gentle but very effective.”

What does Megan Fox use on face? ›

Her regular beauty regimen mostly includes cleansing and moisturizing. She washes her face thoroughly at least twice a day followed by a mild moisturizing with Bulgarian Rose Otto by Epicuren Discovery.

What is the new skin tightening technology? ›

Thermage® FLX uses radiofrequency technology to heat the deep, collagen-rich layers of the skin, while the tip vibrates and cools the surface to help aid in patient comfort. The applied heat separates the water molecules from the fibrous collagen, causing an immediate contraction, resulting in skin tightening.

What truly works on deeper wrinkles on your face? ›

Soft tissue fillers, which include fat, collagen and hyaluronic acid (Restylane, Juvederm, others), can be injected into wrinkles on your face. They plump and smooth wrinkles and furrows. You may experience temporary swelling, redness and bruising in the treated area. The effect of most products is temporary.

What is scientifically proven to reduce wrinkles? ›

AHAs , beta hydroxyl acids and a newer form called polyhydroxy acids have also been shown to be effective in reducing fine lines and wrinkles. Coenzyme Q10. This ingredient may help reduce fine wrinkles around the eyes and protect the skin from sun damage.

What is the best supplement for tightening skin? ›

Vitamin C. Vitamin C is needed for collagen synthesis and also helps protect skin from sun damage ( 19 ). Omega-3 fatty acids. The omega-3 fatty acids found in fatty fish may help increase skin elasticity and have anti-aging effects ( 20 ).

Can you reverse collagen loss in face? ›

There's no such thing as a collagen treatment for facial skin, per se, but there are plenty of cosmetic treatments that can reduce the appearance of fine lines and wrinkles with increased collagen production as a side effect.

What tightens wrinkles on face? ›

Retinol (vitamin A) is the most frequently used ingredient in anti-aging creams. But tretinoin, another form of vitamin A, may be the most effective ingredient to firm the skin on your neck and face.

How do you get rid of deep wrinkles around your mouth? ›

How to get rid of wrinkles around the mouth and chin using medical and aesthetic treatments
  1. Chemical peel. ...
  2. Dermabrasion and microdermabrasion. ...
  3. Microneedling. ...
  4. Platelet-rich plasma. ...
  5. Dermal fillers. ...
  6. Botox. ...
  7. Laser skin resurfacing. ...
  8. Facelift.
Jun 10, 2020

How do Koreans not get wrinkles? ›

Age is no bar for skincare

According to Cho, preventative skincare in Korea begins when you start applying sunscreen or wearing hats and clothing that protect you from sun exposure at six months old. “Not only does this prevent sunburns, but it also hinders sun damage that can contribute to ageing later in life.

Does anything really reduce wrinkles? ›

There are treatments to lessen the appearance of wrinkles and even remove them. Retinoids (tretinoin, Altreno, Retin-A, Renova, Tazorac). Among medical treatments, this is by far the most proven and effective way of bettering signs of aging such as uneven pigmentation, roughness, and wrinkling.

What collagen does Jennifer Aniston use? ›

Vital Proteins® Original Collagen Peptides

Jen Says: "My go-to collagen routine is adding Vital Proteins® Collagen Peptides ($27; shop now) in my morning cup of coffee or smoothie – so easy to use."

Can anything tighten sagging skin? ›

You can go the nonsurgical route and add firming creams or facial exercises to your skincare routine. There are also cosmetic procedures that provide quicker results, such as laser surfacing or ultrasound skin tightening. To find the best solution for you, consult a board-certified dermatologist.

What kills collagen in the face? ›

Sun exposure, smoking and eating too much sugar have been shown to decrease collagen levels, which can further emphasize signs of aging.

Does tapping face stimulate collagen? ›

Just five minutes a day of regular tapping:

plumps the face and smoothes wrinkles by stimulating collagen production; normalizes the activity of oil and sweat glands.


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